NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)

SBIR Phase I, Phase II, Direct to Phase II (NIH only), and Fast-Track (NIH only) grant applications from eligible United States small business concerns (SBCs). The program supports R&D to develop commercial products with majority of research effort by the small business. Phase I establishes technical merit and feasibility; Phase II continues R&D toward commercialization. Clinical trials are optional but not accepted by certain NIH components (NIAMS, NIDCR, NCATS, ORIP) or FDA components (CBER, CDER, HFP, CDRH, CVM). Program Details Department of Health and Human Services is a funding organization that offers the NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) grant program to support research innovation and sbir sttr. This funding opportunity is available nationally and is administered by Department of Health and Human Services through SBIR.gov Open Topics. Organizations seeking funding for research innovation and sbir sttr should review the details below and confirm their eligibility before preparing an application. Eligibility Eligible applicants include for-profit businesses. Organizations that meet the eligibility criteria are encouraged to apply and to review the full program guidelines before submission. Because eligibility rules and funding priorities can change between cycles, applicants should always confirm the current requirements with Department of Health and Human Services or on SBIR.gov Open Topics before investing time in an application. Funding and Timeline The application deadline is April 6, 2027 (165 days remaining). Applicants should allow sufficient time to gather required documentation, including organizational information, project descriptions, budgets, and supporting materials as specified in the program guidelines. Submitting a complete application well ahead of the deadline reduces the risk of disqualification on technical or administrative grounds. Program Focus This grant supports research innovation and sbir sttr. This grant is associated with NAICS industry classifications: 541715. Organizations operating in these sectors are encouraged to review eligibility. Funded projects are expected to demonstrate measurable outcomes aligned with the program's stated objectives. Grant recipients may be required to submit progress reports and final evaluations as a condition of the award, and to retain records for audit and compliance purposes. How to Apply Eligible organizations can apply through SBIR.gov Open Topics. Create a free organization profile on GrantRegister to see whether this grant matches your organization's NAICS code, entity type, location, and focus area, and to receive a weekly digest of every open grant you qualify for. GrantRegister maintains a complete, authoritative registry of US federal, state, and foundation grant opportunities — matched automatically to your organization profile and delivered every Monday.

Eligibility

• Programs related to sbir

Award details

Applications close on April 6, 2027 (165 days remaining).

Categories

Research Innovation · Sbir Sttr