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Federal Agency · Office of Science

The Genesis Mission: Transforming Science and Energy with AI

Posted March 17, 2026

Funding

$500K – $16M

Closes

December 17, 2026

NAICS

541715

The DOE Office of Science (SC), Office of Critical Minerals and Energy Innovation (CMEI), Office of Environmental Management (EM), Office of Nuclear Energy (NE), Office of Electricity (OE), and Hydrocarbons and Geothermal Office (HGEO) hereby announce interest in receiving applications from interdisciplinary teams addressing the Genesis Mission National Science and Technology Challenges to accelerate scientific discovery and research and development (R&D) workflows using novel artificial intelligence (AI) models and frameworks. By achieving AI advantage, these teams will advance the DOE's mission and ensure America’s security and prosperity by addressing energy, environmental, and nuclear challenges through science and technology. Teams are encouraged to leverage the extensive scientific and data resources of the DOE/National Nuclear Security Administration (NNSA), the National Laboratories, U.S. industry, and academia. The resulting AI models and workflows, if successful, may be integrated into the American Science Cloud.

Eligibility

Funded by DOE-SC, Programs related to artificial intelligence, Programs related to manufacturing, Programs related to advanced manufacturing, Programs related to semiconductor, and Programs related to biotechnology.

Award details

Award range: $500K – $16M. Applications close on December 17, 2026 (233 days remaining).

Categories

Environment Energy · Rd Grants · Research Innovation

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View application on Grants.gov·Source: Grants.gov·Last seen Apr 28, 2026