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This grant closed on September 9, 2026. It remains listed for reference — similar grants still accepting applications are shown below.

Federal Agency · National Institutes of Health

NIH Director’s Pioneer Award (DP1 Clinical Trial Optional)

Last updated: September 10, 2026

Posted June 29, 2026

Funding

$700K

Closes

September 9, 2026

NAICS

541714

Similar grants still open

The NIH Director"s Pioneer Award supports individual scientists of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. To be considered pioneering, the proposed research must reflect substantially different scientific directions from those already being pursued in the investigator"s research program or elsewhere. Applications in all topics relevant to the broad mission of NIH are welcome. Research may involve basic, translational, or clinical research. The NIH Director"s Pioneer Award is a component of the High-Risk, High-Reward Research (HRHR) program of the NIH Common Fund. Program Details National Institutes of Health is a federal agency that offers the NIH Director’s Pioneer Award (DP1 Clinical Trial Optional) grant program to support eligible programs and projects. This funding opportunity is available nationally and is administered by National Institutes of Health through Grants.gov. Organizations seeking funding for eligible programs and projects should review the details below and confirm their eligibility before preparing an application. Eligibility Eligible applicants include government agencies and municipalities, educational institutions, tribal governments and Native American organizations, and eligible organizations. Organizations that meet the eligibility criteria are encouraged to apply and to review the full program guidelines before submission. Because eligibility rules and funding priorities can change between cycles, applicants should always confirm the current requirements with National Institutes of Health or on Grants.gov before investing time in an application. Funding and Timeline Funding available: $700K. Applications are due by September 9, 2026. Applicants should allow sufficient time to gather required documentation, including organizational information, project descriptions, budgets, and supporting materials as specified in the program guidelines. Submitting a complete application well ahead of the deadline reduces the risk of disqualification on technical or administrative grounds. Program Focus This grant supports eligible programs and projects. This grant is associated with NAICS industry classifications: 541714, 621111, 621112, 622. Organizations operating in these sectors are encouraged to review eligibility. Funded projects are expected to demonstrate measurable outcomes aligned with the program's stated objectives. Grant recipients may be required to submit progress reports and final evaluations as a condition of the award, and to retain records for audit and compliance purposes. How to Apply Eligible organizations can apply through Grants.gov. Create a free organization profile on GrantRegister to see whether this grant matches your organization's NAICS code, entity type, location, and focus area, and to receive a weekly digest of every open grant you qualify for. GrantRegister maintains a complete, authoritative registry of US federal, state, and foundation grant opportunities — matched automatically to your organization profile and delivered every Monday.

Eligibility

  • Funded by NIH

Award details

Award range: $700K. Applications close on September 9, 2026.

Categories

Not categorized

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Applications closed — listing kept for reference.·Source: Grants.gov·Last seen Sep 8, 2026

GrantRegister provides information, not advice. Eligibility requirements and deadlines are set by the funder and can change without notice. Confirm eligibility, deadlines, and requirements with National Institutes of Health before applying.